Most Expensive Drugs Currently Billed Through the U.S. Pharmacy Benefit

Medication Primary Indication Number of Potential U.S. Patients Cost per 30-day Rx
Ceprotin Protein C deficiency  20 > $70K
Carbaglu NAGS (enzyme) deficiency  20
Erwinaze E. coli-sensitive acute lymphoblastic leukemia  1,000
NovoSeven RT Hemophilia A & B with inhibitors 5,000
Feiba NF Hemophilia A & B with inhibitors 5,000
Adagen Adenosine deaminase (enzyme) deficiency in certain patients with SCID 50
Mononine Hemophilia B 4,000 $50K - $70K
Naglazyme Mucopolysaccharidosis VI (enzyme deficiency)  50
Cinryze Hereditary angioedema 8,000
Berinert Hereditary angioedema 8,000
$40K - $50K
H.P. Acthar Infantile spasms  9,000
Alphanate Hemophilia A, von Willebrand disease  50,000
$35K - $40K
Rixubis Hemophilia B  4,000
Aldurazyme Mucopolysaccharidosis I (Enzyme deficiency) 3,000
Soliris Paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome  7,000
Vimizim Mucopolysaccharidosis IVA (enzyme deficiency)  1,500
AlphaNine SD Hemophilia B 4,000
$30K - $35K
Harvoni Hepatitis C, genotype 1 2,400,000
Elaprase Mucopolysaccharidosis II (enzyme deficiency) 50,000
Myalept Leptin deficiency in lipodystrophy 500
Zavesca Gaucher disease type 1   8,000
Ravicti Urea cycle disorders   1,500
Kogenate FS Hemophilia A 12,500
$28K - $30K
Lumizyme Pompe disease 8,000
Gattex Short bowel syndrome 1,500
Sovaldi Hepatitis C, genotype 1 2,400,000